Main inclusion criteria:
- Clinical diagnosis of PN for at least 6 months with Pruriginous nodular lesions on upper limbs, trunk, and/or lower limbs. At least 20 nodules on the entire body with a bilateral distribution with IGA score ≥ 3.
- Severe pruritus defined as ≥ 7 on the PP NRS.
- Lack of any other primary pruritic skin condition.
Dr. Jonathan Silverberg
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