Education
BS, American University of Beirut
MA, George Washington University
MD, American University of Beirut
Certifications
American Board of Psychiatry and Neurology
Added Qualifications in Clinical Neurophysiology and Epilepsy
Added Qualifications in Epilepsy
Residencies
New York University - New York NY
Fellowships
Johns Hopkins University - Baltimore, MD
Clinical / Research Interests
Epilepsy
Medication-resistant Epilepsy
Epilepsy Surgery
Deep Brain Stimulation
Brain Mapping
Language
Memory
Consciousness
Antiseizure Medications
Biography

Mohamad Zakaria Koubeissi, MD, FAAN, FANA, FAES is Professor of Neurology, Director of the Epilepsy Center, at George Washington University in Washington, DC. Dr. Koubeissi earned his bachelor's degree with Distinction in Mathematics (1995) and his medical degree (1999) from the American University of Beirut (AUB) in Lebanon. He spent a year as a postdoctoral research fellow at AUB before he pursued his clinical training in Neurology at Upstate Medical University in Syracuse, NY (2000-2002), New York University in New York, NY (2002-2004), and in Epilepsy at Johns Hopkins University in Baltimore, MD (2004-2006). He was on faculty at Case Western Reserve University in Cleveland, OH for 6 years before he joined George Washington University in 2012. He has also earned an MA degree in English Literature from George Washington University in Washington, DC.

During, and after, his training, Dr. Koubeissi has started new lines of research projects in epilepsy. He has lectured on the medical and surgical treatment of intractable epilepsy all over the United States as well as in Europe, Latin America, and the Middle East. He has published over 100 peer-reviewed papers in esteemed medical journals and has edited four books on epilepsy. He directs the annual Epilepsy Board review Course and the world-renowned, live-streaming monthly Epilepsy Grand Rounds at GWU, is a reviewer for a number of major journals, Fellow of both the AAN and the ANA, and has earned numerous other honors, including the Innovation Award from the School of Engineering at Case Western in 2012.

Dr. Koubeissi's research on consciousness and epilepsy was featured in a National Geographic documentary that aired in November 2015 all over the world in more than 50 languages. He has been elected vice chair of the Epilepsy Section at the American Academy of Neurology and is currently the second vice chair of the Scientific Program Committee at the American Epilepsy Society.

Dr. Koubeissi is fluent in English and Arabic.

Listen to Dr. Mohamad Koubeissi's podcast.

Articles from 2022

 

Common functional connectivity alterations in focal epilepsies identified by machine learning.
Gholipour T, You X, Stufflebeam SM, Loew M, Koubeissi MZ, Morgan VL, Gaillard WD.Epilepsia. 2022 Mar;63(3):629-640. doi: 10.1111/epi.17160. Epub 2022 Jan 4.PMID: 34984672

The Temporal Lobe as a Symptomatogenic Zone in Medial Parietal Lobe Epilepsy.
Jaafar N, Bhatt A, Eid A, Koubeissi MZ.Front Neurol. 2022 Mar 15;13:804128. doi: 10.3389/fneur.2022.804128. eCollection 2022.PMID: 35370889 Review.

The Neural Networks Underlying the Illusion of Time Dilation.
Sheikh MM, Koubeissi MZ, Spencer DD, Alkawadri R.Ann Neurol. 2022 Feb;91(2):295-297. doi: 10.1002/ana.26277. Epub 2021 Dec 13.PMID: 34841572 No abstract available.

Low-frequency stimulation of a fiber tract in bilateral temporal lobe epilepsy.
Koubeissi MZ, Joshi S, Eid A, Emami M, Jaafar N, Syed T, Foreman PJ, Sheth A, Amdur R, Bou Nasif M, Puente AN, Aly R, Chen H, Becker A, Gholipour T, Makke Y, Elmashad A, Gagnon L, Durand DM, Gaillard WD, Shields DC.Epilepsy Behav. 2022 May;130:108667. doi: 10.1016/j.yebeh.2022.108667. Epub 2022 Mar 26.PMID: 35344808 Clinical Trial.

The End Justifies the Means-A Call for Nuance in the Increasing Nationwide Adoption of Stereoelectroencephalography Over Subdural Electrode Monitoring in the Surgical Evaluation of Intractable Epilepsy.
Oluigbo CO, Gaillard WD, Koubeissi MZ.JAMA Neurol. 2022 Mar 1;79(3):221-222. doi: 10.1001/jamaneurol.2021.4994.PMID: 35040868 No abstract available.

 

Articles from 2021

Epilepsy - from mysticism to science.
Bou Nasif M, Koubeissi M, Azar NJ.Rev Neurol (Paris). 2021 Nov;177(9):1047-1058. doi: 10.1016/j.neurol.2021.01.021. Epub 2021 Jul 1.PMID: 34218946 Review.

Stimulating Solutions for Intractable Epilepsy.
Denison T, Koubeissi M, Krook-Magnuson E, Mogul D, Worrell G, Schevon C.Epilepsy Curr. 2021 Apr 30;21(5):15357597211012466. doi: 10.1177/15357597211012466. Online ahead of print.PMID: 33926248 

Seizure recurrence after prolonged seizure control: Patterns and risk factors.
Chen H, Amdur R, Pauldurai J, Koubeissi M.Epilepsy Behav. 2021 Oct 11;124:108330. doi: 10.1016/j.yebeh.2021.108330. Online ahead of print.PMID: 34649159

Multifocal myoclonus as a presentation of levetiracetam toxicity.
Bou Nasif M, Varade S, Koubeissi MZ.Clin Neurophysiol Pract. 2021 Nov 7;6:281-284. doi: 10.1016/j.cnp.2021.10.004. eCollection 2021.PMID: 34877439 

Human hippocampal connectivity is stronger in olfaction than other sensory systems.
Zhou G, Olofsson JK, Koubeissi MZ, Menelaou G, Rosenow J, Schuele SU, Xu P, Voss JL, Lane G, Zelano C.Prog Neurobiol. 2021 Jun;201:102027. doi: 10.1016/j.pneurobio.2021.102027. Epub 2021 Feb 25.PMID: 33640412

Temporal lobe epilepsy with a contralateral parietal seizure-onset zone.
AlGaeed M, Javan R, Shields DC, Gholipour T, Koubeissi MZ.Epileptic Disord. 2021 Oct 1;23(5):787-792. doi: 10.1684/epd.2021.1310.PMID: 34519650

Clinical and genomic analysis of a large Chinese family with familial cortical myoclonic tremor with epilepsy and SAMD12 intronic repeat expansion.
Zhou Y, Sood R, Wang Q, Carrington B, Park M, Young AC, Birnbaum D, Liu Z, Ashizawa T, Mullikin JC, Koubeissi MZ, Liu P.Epilepsia Open. 2021 Feb 2;6(1):102-111. doi: 10.1002/epi4.12450. eCollection 2021 Mar.PMID: 33681653 

Safety and Efficacy of Natalizumab as Adjunctive Therapy for People With Drug-Resistant Epilepsy: A Phase 2 Study.
French JA, Cole AJ, Faught E, Theodore WH, Vezzani A, Liow K, Halford JJ, Armstrong R, Szaflarski JP, Hubbard S, Patel J, Chen K, Feng W, Rizzo M, Elkins J, Knafler G, Parkerson KA; OPUS Study Group.Neurology. 2021 Nov 2;97(18):e1757-e1767. doi: 10.1212/WNL.0000000000012766. Epub 2021 Sep 14.PMID: 34521687 Clinical Trial.

The Neural Networks Underlying the Illusion of Time Dilation.
Sheikh MM, Koubeissi MZ, Spencer DD, Alkawadri R.Ann Neurol. 2022 Feb;91(2):295-297. doi: 10.1002/ana.26277. Epub 2021 Dec 13.PMID: 34841572 No abstract available.

Articles From 2020

Stereotactic electroencephalography.
Gholipour T, Koubeissi MZ, Shields DC.Clin Neurol Neurosurg. 2020 Feb;189:105640. doi: 10.1016/j.clineuro.2019.105640. Epub 2019 Dec 16.PMID: 31865060 Review.

Epileptogenesis-induced changes of hippocampal-piriform connectivity.
Skopin MD, Bayat A, Kurada L, Siddu M, Joshi S, Zelano CM, Koubeissi MZ.Seizure. 2020 Oct;81:1-7. doi: 10.1016/j.seizure.2020.07.008. Epub 2020 Jul 10.PMID: 32682283  

Editorial: The piriform cortex in epilepsy.
Koubeissi MZ.Exp Neurol. 2020 Jul;329:113313. doi: 10.1016/j.expneurol.2020.113313. Epub 2020 Apr 15.PMID: 32325290 No abstract available.

Antiepileptic effects of electrical stimulation of the piriform cortex.
Kurada L, Bayat A, Joshi S, Chahine A, Koubeissi MZ.Exp Neurol. 2020 Mar;325:113070. doi: 10.1016/j.expneurol.2019.113070. Epub 2019 Nov 25.PMID: 31778664 Review.

Seizure symptoms and ambulatory EEG findings: incidence of epileptiform discharges.
Chen H, Koubeissi M, Aziz S, Slater JD, Al Bunni H, Khan MT, Ali NY, Khan FA, Alnobani A, Hussain FM, Syed AU, Fares A, Iqbal T, Syed TU.Epileptic Disord. 2020 Dec 1;22(6):752-758. doi: 10.1684/epd.2020.1220.PMID: 33331277 

Anticipation-induced delta phase reset improves human olfactory perception.
Arabkheradmand G, Zhou G, Noto T, Yang Q, Schuele SU, Parvizi J, Gottfried JA, Wu S, Rosenow JM, Koubeissi MZ, Lane G, Zelano C.PLoS Biol. 2020 May 26;18(5):e3000724. doi: 10.1371/journal.pbio.3000724. eCollection 2020 May.PMID: 32453719 

Using 3D-Printed Mesh-Like Brain Cortex with Deep Structures for Planning Intracranial EEG Electrode Placement.
Javan R, Schickel M, Zhao Y, Agbo T, Fleming C, Heidari P, Gholipour T, Shields DC, Koubeissi M.J Digit Imaging. 2020 Apr;33(2):324-333. doi: 10.1007/s10278-019-00275-3.PMID: 31512018 

The effects of ammonia stimulation on kainate-induced status epilepticus and anterior piriform cortex electrophysiology.
Joshi S, Bayat A, Jones A, Xiao X, Koubeissi MZ.Epilepsy Behav. 2020 Mar;104(Pt A):106885. doi: 10.1016/j.yebeh.2019.106885. Epub 2020 Jan 11.PMID: 31935647

Seizure Occurrences: Patient Report, Scalp EEG, and RNS Electrocorticography Findings.
Chen H, Koubeissi M.J Clin Neurophysiol. 2020 Jul;37(4):306-309. doi: 10.1097/WNP.0000000000000684.PMID: 32022773

Articles From 2019

Electroencephalography in Epilepsy Evaluation.
Chen H, Koubeissi MZ.Continuum (Minneap Minn). 2019 Apr;25(2):431-453. doi: 10.1212/CON.0000000000000705.PMID: 30921017 Review.

Stereotactic electroencephalography.
Gholipour T, Koubeissi MZ, Shields DC.Clin Neurol Neurosurg. 2020 Feb;189:105640. doi: 10.1016/j.clineuro.2019.105640. Epub 2019 Dec 16.PMID: 31865060 Review.

The Claustrum in Relation to Seizures and Electrical Stimulation.
Kurada L, Bayat A, Joshi S, Koubeissi MZ.Front Neuroanat. 2019 Feb 12;13:8. doi: 10.3389/fnana.2019.00008. eCollection 2019.PMID: 30809132  Review. 

Antiepileptic effects of electrical stimulation of the piriform cortex.
Kurada L, Bayat A, Joshi S, Chahine A, Koubeissi MZ.Exp Neurol. 2020 Mar;325:113070. doi: 10.1016/j.expneurol.2019.113070. Epub 2019 Nov 25.PMID: 31778664 Review.

Seize the Day for a Day With No Seizures: Modifiable Midlife Risk Factors Identified.
Koubeissi M.Epilepsy Curr. 2019 Jan;19(1):27-28. doi: 10.1177/1535759718822041. Epub 2019 Jan 30.PMID: 30838917 

Outcome of ambulatory video-EEG monitoring in a ˜10,000 patient nationwide cohort.
Syed TU, LaFrance WC Jr, Loddenkemper T, Benbadis S, Slater JD, El-Atrache R, AlBunni H, Khan MT, Aziz S, Ali NY, Khan FA, Alnobani A, Hussain FM, Syed AU, Koubeissi MZ.Seizure. 2019 Mar;66:104-111. doi: 10.1016/j.seizure.2019.01.018.PMID: 30910235 

Yield and cost-effectiveness of tilt table tests combined with video-EEG.
Chen H, Mercader M, AlGaeed M, Koubeissi M.Epileptic Disord. 2019 Dec 1;21(6):555-560. doi: 10.1684/epd.2019.1109.PMID: 31843734 

Sex influences the frequency of the posterior basic alpha rhythm in patients with epilepsy.
Stephani C, Khan A, Koubeissi M, Paulus W.Clin Neurophysiol Pract. 2019 Apr 26;4:85-89. doi: 10.1016/j.cnp.2019.04.002. eCollection 2019.PMID: 31193042 

Articles From 2018

Uncertainties from a worldwide survey on antiepileptic drug withdrawal after seizure remission.
Bartolini L, Majidi S, Koubeissi MZ.Neurol Clin Pract. 2018 Apr;8(2):108-115. doi: 10.1212/CPJ.0000000000000441.PMID: 29708173 

A pilot study of the role of the claustrum in attention and seizures in rats.
Bayat A, Joshi S, Jahan S, Connell P, Tsuchiya K, Chau D, Syed T, Forcelli P, Koubeissi MZ.Epilepsy Res. 2018 Feb;140:97-104. doi: 10.1016/j.eplepsyres.2018.01.006. Epub 2018 Jan 5.PMID: 29324357

Risk of Unnatural Mortality in Epilepsy.
Koubeissi M.Epilepsy Curr. 2018 Nov-Dec;18(6):365-366. doi: 10.5698/1535-7597.18.6.365.PMID: 30568548  No abstract available.

When the Waves Become Rainbows: Improving Seizure Detection in the Pediatric ICU.
Koubeissi M.Epilepsy Curr. 2018 Mar-Apr;18(2):89-91. doi: 10.5698/1535-7597.18.2.89.PMID: 29670484  No abstract available.

Seizures in Tuberous Sclerosis: Mechanism-Based Interventions EXIST.
Koubeissi M.Epilepsy Curr. 2018 Jan-Feb;18(1):39-41. doi: 10.5698/1535-7597.18.1.39.PMID: 29844762  No abstract available.

Women With Epilepsy and Control Women: Two Peas in a WEPOD.
Koubeissi M.Epilepsy Curr. 2018 Sep-Oct;18(5):311-312. doi: 10.5698/1535-7597.18.5.311.PMID: 30464731  No abstract available.

Articles From 2017

Hypercognitive seizures - Proposal of a new term for the phenomenon forced thinking in epilepsy.
Stephani C, Koubeissi M.Epilepsy Res. 2017 Aug;134:63-71. doi: 10.1016/j.eplepsyres.2017.02.013.PMID: 28595758 Review.

Anticonvulsant Effects of Cannabidiol in Dravet Syndrome.
Koubeissi M.Epilepsy Curr. 2017 Sep-Oct;17(5):281-282. doi: 10.5698/1535-7597.17.5.281.PMID: 29225539  No abstract available.

Resting Connectivity in Non-lesional Temporal Lobe Epilepsy.
Koubeissi M.Epilepsy Curr. 2017 Jul-Aug;17(4):219-220. doi: 10.5698/1535-7597.17.4.219.PMID: 29225523  No abstract available.

Yawning induced by focal electrical stimulation in the human brain.
Joshi S, Bayat A, Gagnon L, Shields DC, Koubeissi MZ.Epilepsy Behav. 2017 Jan;66:1-3. doi: 10.1016/j.yebeh.2016.09.006. Epub 2016 Dec 11.PMID: 27960124

Unmasking of myoclonus by lacosamide in generalized epilepsy.
Birnbaum D, Koubeissi M.Epilepsy Behav Case Rep. 2016 Nov 16;7:28-30. doi: 10.1016/j.ebcr.2016.09.006. eCollection 2017.PMID: 28239547 

Effects of low-frequency electrical stimulation of the anterior piriform cortex on kainate-induced seizures in rats.
Bayat A, Skopin MD, Joshi S, Siddu M, Mukharesh L, Jahan S, Tsuchiya K, Connell P, Younes N, Koubeissi MZ.Epilepsy Behav. 2017 Jul;72:1-7. doi: 10.1016/j.yebeh.2017.04.002. Epub 2017 May 28.PMID: 28564587

Prevalence and Risk Factors for Early Seizure in Patients with Traumatic Brain Injury: Analysis from National Trauma Data Bank.
Majidi S, Makke Y, Ewida A, Sianati B, Qureshi AI, Koubeissi MZ.Neurocrit Care. 2017 Aug;27(1):90-95. doi: 10.1007/s12028-016-0363-6.PMID: 28000125

Acute and spontaneous seizure onset zones in the intraperitoneal kainic acid model.
Connell P, Bayat A, Joshi S, Koubeissi MZ.Epilepsy Behav. 2017 Mar;68:66-70. doi: 10.1016/j.yebeh.2016.12.017. Epub 2017 Jan 19.PMID: 28109992

Dropping the Sectioning of the Anterior Corpus Callosum for Drop Attacks.
Koubeissi M.Epilepsy Curr. 2017 Sep-Oct;17(5):291-292. doi: 10.5698/1535-7597.17.5.291.PMID: 29225543  No abstract available.

Articles From 2016

Women with epilepsy.
Sharma A, Boller F, Koubeissi M.Funct Neurol. 2016 Jul-Sep;31(3):125-6. doi: 10.11138/fneur/2016.31.3.125.PMID: 27678204  No abstract available.

Electroencephalography (EEG): An Introductory Text and Atlas of Normal and Abnormal Findings in Adults, Children, and Infants [Internet].
Britton JW, Frey LC, Hopp JL, Korb P, Koubeissi MZ, Lievens WE, Pestana-Knight EM, St. Louis EK, authors. St. Louis EK, Frey LC, editors.Chicago: American Epilepsy Society; 2016.PMID: 27748095 Free Books & Documents. Review.

Unusual atypical language lateralization.
Khan MT, Oghlakian R, Koubeissi MZ.Epilepsy Behav Case Rep. 2016 Mar 9;6:73-4. doi: 10.1016/j.ebcr.2016.01.007. eCollection 2016.PMID: 27668182  

Multiple hippocampal transections for intractable hippocampal epilepsy: Seizure outcome.
Koubeissi MZ, Kahriman E, Fastenau P, Bailey C, Syed T, Amina S, Miller J, Munyon C, Tanner A, Karanec K, Tuxhorn I, Lüders H.Epilepsy Behav. 2016 May;58:86-90. doi: 10.1016/j.yebeh.2016.03.004. Epub 2016 Apr 8.PMID: 27064827

Pay Attention: Mindfulness in Epilepsy.
Koubeissi M.Epilepsy Curr. 2016 Jul-Aug;16(4):245-6. doi: 10.5698/1535-7511-16.4.245.PMID: 27582662  No abstract available.

Intravenous Clonazepam in Status Epilepticus.
Koubeissi M.Epilepsy Curr. 2016 Mar-Apr;16(2):89-90. doi: 10.5698/1535-7511-16.2.89.PMID: 27073337  No abstract available.

Yawning induced by focal electrical stimulation in the human brain.
Joshi S, Bayat A, Gagnon L, Shields DC, Koubeissi MZ.Epilepsy Behav. 2017 Jan;66:1-3. doi: 10.1016/j.yebeh.2016.09.006. Epub 2016 Dec 11.PMID: 27960124

Unmasking of myoclonus by lacosamide in generalized epilepsy.
Birnbaum D, Koubeissi M.Epilepsy Behav Case Rep. 2016 Nov 16;7:28-30. doi: 10.1016/j.ebcr.2016.09.006. eCollection 2017.PMID: 28239547 

Does Seizure Duration Predict the Termination of a Seizure Cluster?
Koubeissi M.Epilepsy Curr. 2016 Nov-Dec;16(6):391-392. doi: 10.5698/1535-7511-16.6.391.PMID: 27857620  No abstract available. 

A white matter tract mediating awareness of speech.
Koubeissi MZ, Fernandez-Baca Vaca G, Maciunas R, Stephani C.Neurology. 2016 Jan 12;86(2):177-9. doi: 10.1212/WNL.0000000000002246. Epub 2015 Dec 7.PMID: 26643545

Articles from 2015 and Prior

Levetiracetam-induced pancytopenia.
Alzahrani T, Kay D, Alqahtani SA, Makke Y, Lesky L, Koubeissi MZ.Epilepsy Behav Case Rep. 2015 Jul 24;4:45-7. doi: 10.1016/j.ebcr.2015.06.001. eCollection 2015.PMID: 26744695 

A white matter tract mediating awareness of speech.
Koubeissi MZ, Fernandez-Baca Vaca G, Maciunas R, Stephani C.Neurology. 2016 Jan 12;86(2):177-9. doi: 10.1212/WNL.0000000000002246. Epub 2015 Dec 7.PMID: 26643545

3D for Define Implantation Targets, Distinguish Eloquent Cortex, or Desist From Invasive Monitoring.
Koubeissi M.Epilepsy Curr. 2015 Nov-Dec;15(6):338-9. doi: 10.5698/1535-7511-15.6.338.PMID: 26633956  No abstract available. 

Proceedings of the Seventh International Workshop on Advances in Electrocorticography.
Ritaccio A, Matsumoto R, Morrell M, Kamada K, Koubeissi M, Poeppel D, Lachaux JP, Yanagisawa Y, Hirata M, Guger C, Schalk G.Epilepsy Behav. 2015 Oct;51:312-20. doi: 10.1016/j.yebeh.2015.08.002. Epub 2015 Aug 29.PMID: 26322594 

Between the Pulse Generator and the Anterior Thalamic Nucleus: The Light at the End of the Tunnel.
Koubeissi MZ.Epilepsy Curr. 2015 Jul-Aug;15(4):183-4. doi: 10.5698/1535-7511-15.4.183.PMID: 26316862  No abstract available.

The piriform, perirhinal, and entorhinal cortex in seizure generation.
Vismer MS, Forcelli PA, Skopin MD, Gale K, Koubeissi MZ.Front Neural Circuits. 2015 May 29;9:27. doi: 10.3389/fncir.2015.00027. eCollection 2015.PMID: 26074779  Review. 

Differences of Intracranial Electrical Stimulation Thresholds in the Human Brain.
Stephani C, Koubeissi M.Brain Stimul. 2015 Jul-Aug;8(4):724-9. doi: 10.1016/j.brs.2015.02.011. Epub 2015 Mar 10.PMID: 25842075

Seizures worsen stroke outcome: new evidence from a large sample.
Koubeissi M.Epilepsy Curr. 2015 Jan-Feb;15(1):30-1. doi: 10.5698/1535-7597-15.1.30.PMID: 25678885  No abstract available.

Factitious psychogenic nonepileptic paroxysmal episodes.
Romano A, Alqahtani S, Griffith J, Koubeissi MZ.Epilepsy Behav Case Rep. 2014 Oct 10;2:184-5. doi: 10.1016/j.ebcr.2014.08.006. eCollection 2014.PMID: 25667902 

Safety and efficacy of adjunctive lacosamide among patients with partial-onset seizures in a long-term open-label extension trial of up to 8 years.
Rosenfeld W, Fountain NB, Kaubrys G, Ben-Menachem E, McShea C, Isojarvi J, Doty P; SP615 Study Investigators.Epilepsy Behav. 2014 Dec;41:164-70. doi: 10.1016/j.yebeh.2014.09.074. Epub 2014 Oct 27.PMID: 25461210 Clinical Trial.

Monotherapy in newly diagnosed epilepsy: levetiracetam versus standard anticonvulsants.
Koubeissi MZ.Epilepsy Curr. 2014 Sep;14(5):255-6. doi: 10.5698/1535-7597-14.5.255.PMID: 25346630  No abstract available.

Lacosamide-induced rash.
Koubeissi MZ, Vismer M, Ehrlich A.Epileptic Disord. 2014 Sep;16(3):380-3. doi: 10.1684/epd.2014.0667.PMID: 25035958 

Pharmacoresistant epilepsy in hypomelanosis of Ito: palliative surgical treatment with modified anatomic posterior quadrantic resection.
Manjila S, Miller BR, Goodman A, Bahuleyan B, Basha M, Munyon C, Cohen ML, Koubeissi M, Miller JP.Clin Neurol Neurosurg. 2014 Aug;123:15-7. doi: 10.1016/j.clineuro.2014.04.024. Epub 2014 May 4.PMID: 25012005 No abstract available.

Electrical stimulation of a small brain area reversibly disrupts consciousness.
Koubeissi MZ, Bartolomei F, Beltagy A, Picard F.Epilepsy Behav. 2014 Aug;37:32-5. doi: 10.1016/j.yebeh.2014.05.027. Epub 2014 Jun 24.PMID: 24967698 

Role of ictal baseline shifts and ictal high-frequency oscillations in stereo-electroencephalography analysis of mesial temporal lobe seizures.
Wu S, Kunhi Veedu HP, Lhatoo SD, Koubeissi MZ, Miller JP, Lüders HO.Epilepsia. 2014 May;55(5):690-698. doi: 10.1111/epi.12608. Epub 2014 Apr 11.PMID: 24725106 

Do we need seizure prophylaxis for brain tumor surgery?
Koubeissi M.Epilepsy Curr. 2014 Jan;14(1):24-5. doi: 10.5698/1535-7597-14.1.24.PMID: 24526871  No abstract available. 

Levetiracetam: more evidence of safety in pregnancy.
Koubeissi M.Epilepsy Curr. 2013 Nov;13(6):279-81. doi: 10.5698/1535-7597-13.6.279.PMID: 24348127  No abstract available.

Hemispherectomy: the full half of the glass.
Koubeissi M.Epilepsy Curr. 2013 Sep;13(5):213-4. doi: 10.5698/1535-7597-13.5.213.PMID: 24348108  No abstract available.

Accuracy of frame-based stereotactic depth electrode implantation during craniotomy for subdural grid placement.
Munyon CN, Koubeissi MZ, Syed TU, Lüders HO, Miller JP.Stereotact Funct Neurosurg. 2013;91(6):399-403. doi: 10.1159/000351524. Epub 2013 Oct 9.PMID: 24108242

Neuropathology of the blood-brain barrier in epilepsy: support to the transport hypothesis of pharmacoresistance.
Koubeissi M.Epilepsy Curr. 2013 Jul;13(4):169-71. doi: 10.5698/1535-7597-13.4.169.PMID: 24009480  No abstract available.

Difficult-to-Localize Intractable Focal Epilepsy: An "In-Depth" Look.
Koubeissi MZ.Epilepsy Curr. 2013 Mar;13(2):88-9. doi: 10.5698/1535-7597-13.2.88.PMID: 23646014  No abstract available.

Low-frequency electrical stimulation of a fiber tract in temporal lobe epilepsy.
Koubeissi MZ, Kahriman E, Syed TU, Miller J, Durand DM.Ann Neurol. 2013 Aug;74(2):223-31. doi: 10.1002/ana.23915. Epub 2013 Sep 4.PMID: 23613463

Antiepileptic medications after extratemporal epilepsy surgery: when do we stop?
Koubeissi M.Epilepsy Curr. 2013 Jan;13(1):13-4. doi: 10.5698/1535-7511-13.1.13.PMID: 23447729  No abstract available.

Epilepsy surgery: a broken bridge between utility and utilization.
Koubeissi M.Epilepsy Curr. 2012 Sep;12(5):194-6. doi: 10.5698/1535-7511-12.5.194.PMID: 23118606  No abstract available.

Risk factors associated with death in in-hospital pediatric convulsive status epilepticus.
Loddenkemper T, Syed TU, Ramgopal S, Gulati D, Thanaviratananich S, Kothare SV, Alshekhlee A, Koubeissi MZ.PLoS One. 2012;7(10):e47474. doi: 10.1371/journal.pone.0047474. Epub 2012 Oct 26.PMID: 23110074 

Independent and symmetric seizures from parasagittal cortex: is this a feature of profound hypoglycemia?
Shaikh AG, Gulati D, Wu S, Koubeissi MZ.Epilepsy Behav. 2012 Oct;25(2):263-5. doi: 10.1016/j.yebeh.2012.07.022. Epub 2012 Oct 5.PMID: 23041174 

Visual processing in the inferior temporal cortex: an intracranial event related potential study.
Hitomi T, Koubeissi MZ, Kaffashi F, Turnbull J, Lüders HO.Clin Neurophysiol. 2013 Jan;124(1):164-70. doi: 10.1016/j.clinph.2012.07.002. Epub 2012 Sep 19.PMID: 22999318

Vivid recollection of a past traumatic event: a rare manifestation of temporal lobe seizures.
Koubeissi MZ.Epileptic Disord. 2012 Sep;14(3):325-8. doi: 10.1684/epd.2012.0530.PMID: 22947440 

Modern technology calls for a modern approach to classification of epileptic seizures and the epilepsies.
Lüders HO, Amina S, Baumgartner C, Benbadis S, Bermeo-Ovalle A, Devereaux M, Diehl B, Edwards J, Baca-Vaca GF, Hamer H, Ikeda A, Kaiboriboon K, Kellinghaus C, Koubeissi M, Lardizabal D, Lhatoo S, Lüders J, Mani J, Mayor LC, Miller J, Noachtar S, Pestana E, Rosenow F, Sakamoto A, Shahid A, Steinhoff BJ, Syed T, Tanner A, Tsuji S.Epilepsia. 2012 Mar;53(3):405-11. doi: 10.1111/j.1528-1167.2011.03376.x. Epub 2012 Feb 14.PMID: 22332669  Review.

Requirement of longitudinal synchrony of epileptiform discharges in the hippocampus for seizure generation: a pilot study.
Umeoka SC, Lüders HO, Turnbull JP, Koubeissi MZ, Maciunas RJ.J Neurosurg. 2012 Mar;116(3):513-24. doi: 10.3171/2011.10.JNS11261. Epub 2011 Dec 16.PMID: 22175726

Limitations of NIS database in evaluation of epilepsy surgery morbidity and mortality.
Kaiboriboon K, Schiltz N, Koroukian SM, Lhatoo SD, Koubeissi MZ.Arch Neurol. 2011 Nov;68(11):1483; author reply 1483-4. doi: 10.1001/archneurol.2011.222.PMID: 22084137 No abstract available.

Connectivity between perisylvian and bilateral basal temporal cortices.
Koubeissi MZ, Lesser RP, Sinai A, Gaillard WD, Franaszczuk PJ, Crone NE.Cereb Cortex. 2012 Apr;22(4):918-25. doi: 10.1093/cercor/bhr163. Epub 2011 Jun 29.PMID: 21715651 

Transection of CA3 does not affect memory performance in rats.
Koubeissi MZ, Rashid S, Casadesus G, Xu K, Syed TU, Lüders H, Durand D.Epilepsy Behav. 2011 Jul;21(3):267-70. doi: 10.1016/j.yebeh.2011.04.006. Epub 2011 May 14.PMID: 21576037 

Can semiology predict psychogenic nonepileptic seizures? A prospective study.
Syed TU, LaFrance WC Jr, Kahriman ES, Hasan SN, Rajasekaran V, Gulati D, Borad S, Shahid A, Fernandez-Baca G, Garcia N, Pawlowski M, Loddenkemper T, Amina S, Koubeissi MZ.Ann Neurol. 2011 Jun;69(6):997-1004. doi: 10.1002/ana.22345. Epub 2011 Mar 17.PMID: 21437930 

Efficacy and safety of intravenous lacosamide in refractory nonconvulsive status epilepticus.
Koubeissi MZ, Mayor CL, Estephan B, Rashid S, Azar NJ.Acta Neurol Scand. 2011 Feb;123(2):142-6. doi: 10.1111/j.1600-0404.2010.01430.x. Epub 2010 Oct 10.PMID: 21198444

Functional neuroanatomy of the insular lobe.
Stephani C, Fernandez-Baca Vaca G, Maciunas R, Koubeissi M, Lüders HO.Brain Struct Funct. 2011 Jun;216(2):137-49. doi: 10.1007/s00429-010-0296-3. Epub 2010 Dec 14.PMID: 21153903 

Inpatient video-EEG monitoring: how much shall we review?
Koubeissi MZ, Syed TU.Clin Neurophysiol. 2011 Jun;122(6):1065-6. doi: 10.1016/j.clinph.2010.11.013. Epub 2010 Dec 13.PMID: 21147551 No abstract available.

A case of levetiracetam-induced thrombocytopenia.
Oghlakian R, Nock C, Koubeissi M.Epileptic Disord. 2010 Dec;12(4):335-7. doi: 10.1684/epd.2010.0343. Epub 2010 Nov 16.PMID: 21078583 

Triple pathology in epilepsy: coexistence of cavernous angiomas and cortical dysplasias with other lesions.
Maciunas JA, Syed TU, Cohen ML, Werz MA, Maciunas RJ, Koubeissi MZ.Epilepsy Res. 2010 Sep;91(1):106-10. doi: 10.1016/j.eplepsyres.2010.07.002. Epub 2010 Jul 31.PMID: 2067427. 

Improvement of myoclonic epilepsy in Down syndrome treated with levetiracetam.
Sangani M, Shahid A, Amina S, Koubeissi M.Epileptic Disord. 2010 Jun;12(2):151-4. doi: 10.1684/epd.2010.0306. Epub 2010 May 20.PMID: 20483713 

Visual naming performance after ATL resection: impact of atypical language dominance.
Kovac S, Möddel G, Reinholz J, Alexopoulos AV, Syed T, Koubeissi MZ, Schuele SU, Lineweaver T, Busch RM, Loddenkemper T.Neuropsychologia. 2010 Jun;48(7):2221-5. doi: 10.1016/j.neuropsychologia.2010.03.013. Epub 2010 Mar 15.PMID: 20230846

Hemispherectomy-associated complications from the Kids' Inpatient Database.
Koubeissi MZ, Syed TU, Syed I, Jordan J, Alshekhlee A, Kossoff EH.Epilepsy Res. 2009 Nov;87(1):47-53. doi: 10.1016/j.eplepsyres.2009.07.008. Epub 2009 Sep 5.PMID: 19734011

In-hospital complications of epilepsy surgery: a six-year nationwide experience.
Koubeissi MZ, Puwanant A, Jehi L, Alshekhlee A.Br J Neurosurg. 2009;23(5):524-9. doi: 10.1080/02688690903019589.PMID: 19718552

Symptomatic neurocutaneous melanosis and Dandy-Walker malformation in an adult.
Walbert T, Sloan AE, Cohen ML, Koubeissi MZ.J Clin Oncol. 2009 Jun 10;27(17):2886-7. doi: 10.1200/JCO.2008.21.5830. Epub 2009 Apr 27.PMID: 19398571 No abstract available.

Scotosensitive myoclonic seizures in MERRF.
Koubeissi MZ, Khongkhatithum C, Janus AI, Lüders H.Neurology. 2009 Mar 3;72(9):858. doi: 10.1212/01.wnl.0000343959.15205.52.PMID: 19255416 No abstract available.

Medically intractable seizures originating from the primary somatosensory hand area.
Koubeissi MZ, Maciunas RJ, Tanner A, Lüders HO.Epileptic Disord. 2008 Dec;10(4):339-48. doi: 10.1684/epd.2008.0211.PMID: 19017578 

Analysis of dynamics and propagation of parietal cingulate seizures with secondary mesial temporal involvement.
Koubeissi MZ, Jouny CC, Blakeley JO, Bergey GK.Epilepsy Behav. 2009 Jan;14(1):108-12. doi: 10.1016/j.yebeh.2008.08.021. Epub 2008 Oct 7.PMID: 18809511 

Tolerability and efficacy of oral loading of levetiracetam.
Koubeissi MZ, Amina S, Pita I, Bergey GK, Werz MA.Neurology. 2008 May 27;70(22 Pt 2):2166-70. doi: 10.1212/01.wnl.0000313151.64005.c0.PMID: 18505995 Clinical Trial.

Programmed cell death in the lithium pilocarpine model: evidence for NMDA receptor and ceramide-mediated mechanisms.
Mikati MA, Rizk E, El Dada S, Zeinieh M, Kurdi R, El Hokayem J, Rahmeh A, Koubeissi M, Azzam D, Usta J, El Sabban M, Dbaibo G.Brain Dev. 2008 Sep;30(8):513-9. doi: 10.1016/j.braindev.2008.01.002. Epub 2008 Mar 4.PMID: 18295995 

Being with virtual others: studying social cognition in temporal lobe epilepsy.
Schilbach L, Koubeissi MZ, David N, Vogeley K, Ritzl EK.Epilepsy Behav. 2007 Nov;11(3):316-23. doi: 10.1016/j.yebeh.2007.06.006. Epub 2007 Sep 18.PMID: 17881294

In-hospital mortality of generalized convulsive status epilepticus: a large US sample.
Koubeissi M, Alshekhlee A.Neurology. 2007 Aug 28;69(9):886-93. doi: 10.1212/01.wnl.0000269791.96189.70.PMID: 17724291 

Cerebellar and thalamic stimulation treatment for epilepsy.
Krauss GL, Koubeissi MZ.Acta Neurochir Suppl. 2007;97(Pt 2):347-56. doi: 10.1007/978-3-211-33081-4_40.PMID: 17691323 Review. 

Seizures manifesting as an urge to defecate, with an ictal discharge in the right hemisphere.
Koubeissi MZ, Crone NE, Lesser RP.Epilepsia. 2005 Aug;46(8):1330-2. doi: 10.1111/j.1528-1167.2005.17505.x.PMID: 16060951 

Hippocampal programmed cell death after status epilepticus: evidence for NMDA-receptor and ceramide-mediated mechanisms.
Mikati MA, Abi-Habib RJ, El Sabban ME, Dbaibo GS, Kurdi RM, Kobeissi M, Farhat F, Asaad W.Epilepsia. 2003 Mar;44(3):282-91. doi: 10.1046/j.1528-1157.2003.22502.x.PMID: 12614382