American University of Beirut
American Board of Psychiatry and Neurology
Added Qualifications in Clinical Neurophysiology and Epilepsy
New York University - New York NY
Johns Hopkins University - Baltimore MD
Clinical / Research Interests
Epilepsy Surgery
Deep Brain Stimulation
Antiepileptic Medications

Mohamad Zakaria Koubeissi, MD, FAAN, FANA, FAES is Professor of Neurology, Director of the Epilepsy Center, and Program Director of Epilepsy Fellowship at George Washington University in Washington, DC. Dr. Koubeissi earned his bachelor's degree with Distinction in Mathematics (1995) and his medical degree (1999) from the American University of Beirut (AUB) in Lebanon. He spent a year as a postdoctoral research fellow at AUB before he pursued his clinical training in Neurology at Upstate Medical University in Syracuse, NY (2000-2002), New York University in New York, NY (2002-2004), and in Epilepsy at Johns Hopkins University in Baltimore, MD (2004-2006). He was on faculty at Case Western Reserve University in Cleveland, OH for 6 years before he joined George Washington University in 2012.

During, and after, his training, Dr. Koubeissi has started new lines of research projects in epilepsy. He has lectured on the medical and surgical treatment of intractable epilepsy all over the Unites States as well as in Europe, Latin America, and the Middle East.  He has published his papers in esteemed medical journals, and has edited four books on epilepsy.  He directs the annual Epilepsy Board review Course and the world-renowned, live-streaming monthly Epilepsy Grand Rounds at GWU, is a reviewer for a number of major journals, Fellow of both the AAN and the ANA, and has earned numerous other honors, including the Innovation Award from the School of Engineering at Case Western in 2012.

Dr. Koubeissi’s research on consciousness and epilepsy was featured in a National Geographic documentary that aired in November 2015 all over the world in more than 50 languages.

Listen to Dr. Mohamad Koubeissi's podcast.

Clinical Trials

The primary objective of this study is to evaluate the efficacy of the 3 selected dose regimens of Padsevonil (PSL) administered concomitantly with up to 3 AEDs compared with placebo for treatment of observable focal-onset seizures in subjects with drug-resistant epilepsy.