MD - University of Lisbon Medical School (Lisbon, Portugal)
PhD - Baylor College of Medicine
Clinical / Research Interests
Anatomic Pathology

Antonia R. Sepulveda MD, PhD is professor and chairwoman of the Department of Pathology at George Washington University (GW). She is an expert in gastrointestinal pathology and genomic and molecular diagnostic pathology.  Before joining GW, Dr. Sepulveda was the director of the Division of Gastrointestinal Pathology at Columbia University in New York, where she was also director of the gastrointestinal pathology fellowship program and vice-chair for translational research.

Her clinical practice provides specialized gastrointestinal, biliary and pancreas pathology diagnostic services with integration of molecular testing utilizing genomics and specific tumor biomarkers for personalized cancer management and precision medicine of digestive organ cancers and pre-cancer conditions (esophageal cancer and Barrett's esophagus, gastric, colorectal, pancreas, and biliary pre-cancer lesions and cancers).

Dr. Sepulveda is the medical director of the Genomic and Molecular Pathology division at GW University Department of Pathology, which provides testing for cancer and pre-cancer to meet the needs of precision cancer therapies and molecular virology testing, including COVID-19 SARS-CoV-2 testing.

Dr. Sepulveda's leadership is nationally and internationally recognized. She has been the lead co-chair for the “Molecular testing guidelines for colorectal cancer”, a combined initiative of the American Society for Clinical Pathology, College of American Pathologists Pathology and Laboratory Quality Center, Association for Molecular Pathology and the American Society of Clinical Oncology. Dr. Sepulveda has held many leadership positions and is currently President-elect and member of the Board of Directors of the Association for Molecular Pathology (AMP).

Dr. Sepulveda’s research laboratory receives funding from the NCI and is focused on innovative cancer and pre-cancer biomarkers to improve cancer prevention and treatment. The Sepulveda laboratory integrates cutting edge experimental approaches to define the molecular mechanisms and to discover biomarkers of gastric, esophageal, colorectal and pancreatic cancers and pre-cancer lesions. Dr. Sepulveda has over 170 publications (original research, reviews, chapters and books).