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Shabnam Samankan MD, is an assistant professor of gynecologic, breast and ENT pathology in the Department of Pathology at George Washington University (GW) and the Division Chief of Head & Neck and Endocrine Pathology. Prior to joining GW, Dr. Samankan completed a subspecialty fellowship…
Irena Manukyan MD, PhD is an assistant professor and chief of molecular genetic oncology service in the Department of Pathology at George Washington University (GW). Her expertise is in areas of genomic and molecular diagnostic pathology and cytopathology. Prior to joining GW, she completed a…
Rebecca Yee, Ph.D, D(ABMM) is the Chief of Microbiology and Assistant Professor in the Department of Pathology at George Washington University.
Primary objective: The primary objective of the study is to compare disease-free survival (DFS) of patients with high-risk cutaneous squamous cell carcinoma (CSCC) treated with adjuvant cemiplimab, versus those treated with placebo, after surgery and radiation therapy (RT).
Primary Outcome Measure: Maximum tolerated dose of nivolumab [Time Frame: 56 days]
Will be defined as the starting dose level at which 1/6 subjects experience dose limiting toxicity (DLT) with the next higher dose having at least >= 2 participants encountering DLT. Toxicity data will be…
Have at least 20 nodules of approximately 0.5 to 2 cm. The nodules must be pruritic and present on at least 2 different anatomical locations (not be localized), involve the extremities, with extensor extremity involvement greater than the flexor extremity involvement. Nodules on the head (face and…